Histopathological findings and malignancy of adrenal masses in a pathology and cytology center in Bucaramanga, Santander between 2007 and 2019

Keywords: Malignancy, Pathology, Adrenal Glands, Neoplasm, Neoplasm Metastasis

Abstract

 Introduction Masses found in the adrenal gland can be classified according to their origin, behavior, location, function and manner of diagnosis. In Colombia there are insufficient data describing the frequency and main histopathological characteristics of these lesions. The aim of this manuscript is to describe the main histopathological findings and malignancy of adrenal masses in a medical center specialized in pathology in Bucaramanga, Santander. Methodology. Descriptive and retrospective study. Pathologies of patients of all ages with histopathologic alterations in the adrenal gland were reviewed in a medical center in Bucaramanga, Santander. Results. Seventy-nine adrenal pathologies were reviewed, of which 39 showed adrenal gland lesions. The most frequent lesion found was metastasis (28.2 %), and the most frequent location of the lesion was in the right gland (62.1 %). Conclusion. It is essential that prospective studies be carried out to obtain epidemiological data in order to generate local data.



References

Betancourt VD, Archila EI. Tumores suprarrenales. Revisión bibliográfica. Acta Méd Centro [Internet]. 2014 [citado 17 Mar 2021]; 8(1):[aprox. 10 p.]. Disponible en: http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/59/158

Arnaldi G, Masini A.M, Giacchetti G, Taccaliti A, Faloia E, Mantero F. Adrenal incidentaloma. Braz J Med Biol Res [Internet]. 2000 Oct [cited 2021 Mar 17]; 33(10): 1177-1189. https://doi.org/10.1590/S0100-879X2000001000007

Mannelli M, Colagrande S, Valeri A, Parenti G. Incidental and metastatic adrenal masses. Semin Oncol. 2010;37(6):649–61. https://doi.org/10.1053/j.seminoncol.2010.10.018

Long SE, Miller BS. Adrenocortical cancer treatment. Surg Clin North Am. 2019;99(4):759–71. https://doi.org/10.1016/j.suc.2019.04.012

Kloss RT, Gross MD, Francis IR, Korobkin M, Shapiro B. Incidentally discovered adrenal masses. Endocr Rev. 1995 Aug;16(4):460-84. https://doi.org/10.1210/edrv-16-4-460

Oliveira R, Salvador R, Buñesch L, Sebastià MC, Nicolau C. Manejo y diagnóstico del incidentaloma suprarrenal. Radiología. 2011;53(6):516–30. https://doi.org/10.1016/j.rx.2011.06.006

Román-González A, Agredo-Delgado V, Aristizábal-Barón J, Arizmendy-Acosta D. Prevalencia de mielolipoma como diagnóstico incidental de masas adrenales en tomografías abdominales realizadas en el Hospital Universitario San Vicente Fundación de Medellín. Iatreia. 2018 Dec [cited 2021 Mar 17]; 31(4): 342-350. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-07932018000400342%20%20%20Se%20debe%20corregir%20lo%20demás

Gómez RM, Chervín R, Pardes EM, Lupi S, Surraco ME, Herrera J, et al. Evaluación diagnóstica y terapéutica del incidentaloma suprarrenal. Rev Argent Endocrinol Metab. 2016;53(2):51–8. https://doi.org/10.1016/j.raem.2015.12.001

Fassnacht M, Arlt W, Bancos I, Dralle H, Newell-Price J, Sahdev A et al. Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors. European journal of endocrinology. 2016 Aug;175(2):G1-G34. https://doi.org/10.1530/EJE-16-0467

Hevia M, Abascal JM, Boix P, Dieguez M, Delgado E, Abascal JM. et al. Manejo de la masa suprarrenal: lo que el urólogo debe saber. Actas Urol Esp. 2010 Ago [citado 2021 Mar 17]; 34(7): 586-591. https://doi.org/10.1016/j.acuro.2009.11.010

Vaidya A, Hamrahian A, Bancos I, Fleseriu M, Ghayee HK. The evaluation of incidentally discovered adrenal masses. Endocr Pract. 2019;25(2):178–92. https://doi.org/10.4158/DSCR-2018-0565

Ferreira E, Czepielewski M, Faccin C, Coral M, Furtado A.Prevalência de lesão adrenal incidental em pacientes submetidos a tomografia computadorizada de tórax e abdome em um hospital geral brasileiro. Arq Bras Endocrinol Metab. 2005 Out [citado 2021Mar 17]; 49(5): 769-775. https://doi.org/10.1590/S0004-27302005000500017

Ctvrtlik F, Koranda P, Tichy T. Adrenal disease: a clinical update and overview of imaging. A review. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014;158(1):23–34. https://doi.org/10.5507/bp.2014.010

Domínguez LE, Marín C, Díaz M, Jiménez A. Incidentaloma Suprarrenal: estado de la cuestión. Cir Andal [Internet]. 2014 Marzo; 25(1):53–9. Disponible en: https://www.asacirujanos.com/admin/upfiles/revista/2014/2014-vol25-n1-act6.pdf

Hansel DE, Reuter VE. Adrenal Pathology in the Adult: A Urological Pathologist’s Perspective. Advances in anat. 2016 sep;23(5):273–84. https://doi.org/10.1097/PAP.0000000000000120

De la Quintana A, Martínez G, Arana A, Prieto M, Álvarez I, Martínez L, et al. Cirugía de las metástasis en la glándula suprarrenal: resultados de una serie de 35 pacientes. Cir Esp. 2012;90(10):634–40. https://doi.org/10.1016/j.ciresp.2012.04.013

Alshahrani MA, Bin Saeedan M, Alkhunaizan T, Aljohani IM, Azzumeea FM. Bilateral adrenal abnormalities: imaging review of different entities. Abdom Radiol (NY). 2019;44(1):154–79. https://doi.org/10.1007/s00261-018-1670-5

Angelousi A, Alexandraki KI, Kyriakopoulos G, Tsoli M, Thomas D, Kaltsas G, et al. Neoplastic metastases to the endocrine glands. Endocr Relat Cancer. 2020;27(1):R1–20. https://doi.org/10.1530/ERC-19-0263

Gupta P, Bhalla A, Sharma R. Bilateral adrenal lesions: Bilateral. J Med Imaging Radiat Oncol.2012;56(6):636–45. https://doi.org/10.1111/j.1754-9485.2012.02435.x

Wagnerova H, Lazurova I, Felsoci M. Adrenal metastases. Bratisl Lek Listy. 2013;114(4):237–40. https://doi.org/10.4149/BLL_2013_049

How to Cite
1.
Parra-Serrano GA, Torres-Langhammer MP, Castillo-Díaz AM, García-Ardila ME, Serrano-Gómez S. Histopathological findings and malignancy of adrenal masses in a pathology and cytology center in Bucaramanga, Santander between 2007 and 2019. MedUNAB [Internet]. 2021 Aug. 20 [cited 2026 Mar. 7];24(2):155-68. Available from: https://revistasunabeduco.biteca.online/index.php/medunab/article/view/4054

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Published
2021-08-20

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